Micro-Credential in Toxicology
Programme Overview
The course will deal with brief history of toxicology, dose-response relationships, sources of toxic compounds, exposure classes, movement of toxicants in the environment and different biochemical and molecular methods in toxicology. The course is essential to achieve a comprehensive outline of the classes of toxicants, metabolism of toxicants as well as absorption and distribution of toxicants. This course will help students to acquire information regarding the elimination of toxicants, toxicity assays and organ toxicity. The Toxicology course is designed to offer thorough knowledge of the history of toxicology, dose-response relationships, sources of toxic compounds, exposure classes, movement of toxicants in the environment and different biochemical and molecular methods in toxicology.
Learning Outcomes
On completion of the course participants should be able to:
- Discuss the history of toxicology, dose-response relationships, sources of toxic compounds, exposure classes and movement of toxicants in the environment.
- Execute relevant toxicant analysis and quality assurance principles related to analytical in the laboratories.
- Analyze the nutritional effects, physiological effects, comparative and genetic effects and chemical effects of toxicants.
- Present orally on toxicology.
Course Progression
Credits from this Micro-Credential Programme are transferable to the following full academic programme:
- Degree of Biotechnology
Assessments
- Coursework 80%
- Final Examination 20%
Study Plan for Micro-Credential in Cell Toxicology
Week 1 | INTRODUCTION TO TOXICOLOGY – Definition and scope – Relationship to other sciences and history – A brief history of toxicology – Dose-response relationships – Sources of toxic compounds – Exposure classes – Movement of toxicants in the environment
INTRODUCTION TO BIOCHEMICAL AND MOLECULAR METHODS IN TOXICOLOGY – Cell culture techniques – Molecular techniques – Immunochemical techniques
| Lecture |
Week 2
| TOXICANT ANALYSIS AND QUALITY ASSURANCE PRINCIPLES – General policies related to analytical laboratories – Analytical measurement system – Quality assurance and quality control
Practical 1 – Estimation of target substance through Direct (color tests) in serum sample
CLASSES OF TOXICANTS – Exposure classes – Toxicants in air, water, soil – Toxicants in domestic and occupational settings
Oral presentation 1 | Lecture, practical, presentation |
Week 3
| CLASSES OF TOXICANTS – Classes – Metals – Agricultural chemicals – Food additives and contaminants – Toxins, solvents – Therapeutic drugs
Assignment 1
ABSORPTION AND DISTRIBUTION OF TOXICANT – Mechanism of transport – Physicochemical properties – Relevant routes of absorption and toxico- kinetics
Mid-term test Practical 2 – Estimation of target substance through direct (color tests) in urine sample
| Lecture, practical, assignment, test |
Week 4
| METABOLISM OF TOXICANTS & REACTIVE METABOLITES – Fate of toxicants – Fate of reactive metabolites – Factors affecting toxicity of reactive metabolites
CHEMICAL AND PHYSIOLOGICAL INFLUENCES ON XENOBIOTIC METABOLISM – Nutritional effects – Physiological effects – Comparative and genetic effects – Chemical effects
| Lecture, practical |
Week 5
| ELIMINATION OF TOXICANTS – Transport – Renal elimination – Hepatic elimination – Respiratory elimination
Practical 3 – Estimation of ketones through direct (color tests) in urine sample
TOXIC ACTION – Acute toxicity – Mechanism of acute toxicity
Oral presentation 2
| Lecture, practical, presentation |
Week 6
| CHEMICAL CARCINOGENESIS – Human cancer – Classes of agents associated with Carcinogenesis – General aspect of chemical – carcinogenesis
Assignment 2
ORGAN TOXICITY – Hepatotoxicity – Nephrotoxicity
Practical 4 – Determination of toxicity in water bodies by examining BOD
| Lecture, practical, assignment |
Week 7
| TERATOGENESIS – Principles of teratology – Mammalian embryology overview – Testing protocols
Practical test | Lecture, practical test |
Week 8
| Final Examination | Conclusion Session Awarding of Certificates Presentation by VC or Representative of VC
|
Why Micro-Credential in Lincoln University College (LUC), Malaysia?
Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.