Micro-Credential in Molecular Biology

Duration

2 Months (8 Weeks)

Mode of Delivery

Online/ Face to Face

Online

Application

Programme Overview

Molecular Biology is essential to understand the analysis of the biochemical mechanisms that control the maintenance, expression, and evolution of prokaryotic and eukaryotic genomes. The course is essential to relate the complex processes of life associated with molecular biology. The module stresses on the functions of tissues that depend on the genome of the organism and its expression in different cell types. The module emphasizes on the logic of experimental design and data analysis. The course consists of the topic’s discovery of DNA as genetic material, structure of DNA, RNAs and their structure & function, chromosomes, chromatin and function, replication of DNA, mutations and their consequences, repair of DNA recombination, transposons & retroposons, genetic code, gene regulation during development, genomic & evolution of diversity and others.

Learning Outcomes

On completion of the course participants should be able to:

  • Describe the fundamental principles of Molecular Biology
  • Demonstrate understanding of Molecular Biology effectively in practical activities
  • Discuss about the biological aspects in Molecular Biology in a team
  • Analyze the new innovative ideas and concept related to Molecular Biology
  • Prepare assignment using a variety of resource materials

Course Progression

Credits from this Micro-Credential Programme are transferable to the following full academic programme:

  • Degree of Biotechnology

Assessments

  • Coursework 60%
  • Final Examination 40%

Study Plan for Micro-Credential in Molecular Biology

Week 1

 

INTRODUCTION TO MOLECULAR

BIOLOGY

  • Historical perspective
  • Mendelian Genetics
  • Nature of hereditary material
  • DNA, RNA and protein

 

THE STRUCTURE OF DNA

  • Primary structure: the components of nucleic acids
  • Significance of 5’ and 3’
  • The length of RNA and DNA
  • Structure of DNA

Practical 1

Isolation of DNA

Lecture

Practical

Week 2

 

GENOME ORGANIZATION: FROM

NUCLEOTIDES TO CHROMATIN

  • Eukaryotic genome
  • Bacterial genome
  • Plasmids
  • Organelle genomes: chloroplasts and mitochondria

THE RNA

  • Structure of RNA
  • RNA is involved in a wide range of

cellular processes

  • Historical perspective: the discovery of RNA catalysis

 

Lecture

Tutorial

Week 3

 

THE PROTEIN

  • Introduction
  • The central dogma
  • The genetic code
  • Protein structure
  • Protein function

 

Assignment 1

Oral presentation 1

 

DNA REPLICATION

  • Historical perspective
  • DNA polymerases
  • Nuclear DNA replication in eukaryotic cells
  • Replication of organelle DNA

 

Practical 2

  • Quantitation of DNA by agarose gel electrophoresis

 

Mid-term test

 

Lecture

Practical

Test

Week 4

 

MUTATION AND DNA REPAIR

  • Types of mutations and their phenotypic consequences
  • General classes of DNA damage
  • Repair of single base changes
  • Double-strand break repair

 

TOOLS FOR ANALYZING GENE

EXPRESSION

  • Transient and stable transfection assays 
  • Reporter genes
  • In vitro mutagenesis
  • Analysis at the level of gene transcription & translation

 

Lecture

Tutorial

Week 5

 

TRANSCRIPTION IN PROKARYOTES

  • Transcription and translation are

coupled in bacteria

  • Mechanism of transcription
  • Gene regulation

 

TRANSCRIPTION IN EUKARYOTES

  • Overview of transcriptional regulation
  • Protein-coding gene regulatory elements
  • General transcription machinery
  • Transcription factor

 

Lecture

Tutorial

Week 6

 

THE MECHANISM OF TRANSLATION

  • Ribosome structure and assembly
  • Aminoacyl-tRNA synthetases
  • Initiation of translation
  • Elongation & Termination

 

MOLECULAR TECHNIQUES

  • Introduction
  • Polymerase Chain Reaction
  • Purification of PCR product
  • Gel electrophoresis of purified fragment
  • Other molecular techniques

 

Practical 3

  • Amplification of DNA by Polymerase

Chain Reaction (PCR)

 

Assignment 2

Oral presentation 2

 

Lecture

Practical

Assignment

Presentation

Week 7

 

GENOME ANALYSIS: DNA TYPING,

GENOMICS, AND BEYOND

  • Introduction
  • DNA typing
  • Genomics
  • The human genome project
  • Single nucleotide polymorphism

Practical 4

  • Purification of amplicons

Practical test

 

Lecture

Test

Practical

Week 8

 

Final Examination

Conclusion Session

Awarding of Certificates

Presentation by VC or Representative of VC

 

Why Micro-Credential in Lincoln University College (LUC), Malaysia?

Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.

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