Micro-Credential in Immunology
Programme Overview
The course offers an advance hands-on exposure to carry out isolation and purification of enzymes. The students also have a chance to acquire advanced techniques in protein purification and structural analysis. The students will learn about enzyme kinetics, enzyme catalysis, enzyme regulation and immobilization of enzymes. This course also taught the application of enzymes in various industries. This will help to enhance the students’ knowledge in the subsequent related course like Proteomics, Protein engineering. The course focuses on enzyme kinetics, enzyme catalysis, enzyme regulation, immobilization of enzymes and application of enzymes in various industries
Learning Outcomes
On completion of the course participants should be able to:
- Explain the enzyme, enzyme kinetics, enzyme catalysis, enzyme regulation, immobilization of enzymes, current applications of enzymes, protein structure determination, protein folding and protein purification.
- Perform practical in Enzyme and Protein Purification Technology.
- Prepare assignment using a variety of resource materials.
- Present orally on topics related to Enzyme and Protein Purification Technology.
Course Progression
Credits from this Micro-Credential Programme are transferable to the following full academic programme:
- Master of Biotechnology
Assessments
- Coursework 60%
- Final Examination 40%
Study Plan for Micro-Credential in Immunology
Week 1 | Basic concepts in immunology · Cells of immune system · Innate and acquired immunity · Clonal nature of immune response · Organization and structure of lymphoid organs · Lymphocyte trafficking | Lecture |
Week 2
| Antigen & Antibody Ø Antigens · Compare and contrast immunogen · Antigen and hapten · Factors influencing immunogenicity · Chemical nature of immunogens · Structures of t-independent and t-dependent antigens.
Ø Antibody · Antibody structure and function classes of antibodies
Complement system · Role of the CD3 complex and co-stimulatory molecules – | Lecture |
Week 3
| Vaccine: · Natural, synthetic and genetic vaccine · Problem and prospect associated with development of vaccine for diseases like AIDS Cancer and Malaria Antigen-antibody interactions · Describe the nature of Ag-Ab reactions · Definition of affinity and avidity · Specificity and cross reactivity · Principles of commonly used tests for antigen/antibody reactions
| Lecture, tutorial |
Week 4
| Major Histocompatibility Complex · MHC gene organizations · Class I and class II MHC · Molecules structure and functions nature of polymorphisims in class I and class II MHC molecules
B-cell receptor and T-cell receptor · Generation of diversity · Structure of the t cell receptor for antigen · Genetic basis for the generation of diversity in the TCR
| Lecture, tutorial |
Week 5
| Transplantation · Different types of grafts · Distinguish among the first-set second-set, and chronic rejection · Host vs. Graft rejection · Molecular basis of immune response
Regulation of immune system: · Antigen processing and presentation to T-cells · Activation of B and T-lymphocytes · Cytokines and their role in immune regulation · T-cell regulation · MHC restriction · Immunological tolerance · Immunomodulation · Hematopoiesis and differentiation
| Lecture, practical |
Week 6
| Cell-mediated cytotoxicity: · Mechanism of cytotoxic T cells and NK cells mediated target cell lysis · Antibody dependent cell mediated cytotoxicity · Macrophage mediated cytotoxicity
Failures of Host Defense Mechanisms · Process of invasion of pathogens in the immune system · Inherited immunodeficiency diseases · Acquired immune deficiency syndrome
| Lecture, practical |
Week 7
| Autoimmunity and Transplantation · Autoimmune responses are directed against self-antigens · Responses to alloantigen and · transplant rejection · Self-tolerance and its loss
Allergy and Hypersensitivity · Effector mechanisms in allergic reactions and IgE · Hypersensitivity diseases
| Lecture, practical |
Week 8
| Final Examination | Conclusion Session Awarding of Certificates Presentation by VC or Representative of VC
|
Why Micro-Credential in Lincoln University College (LUC), Malaysia?
Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.