Micro-Credential in Bioinformatics

Duration

2 Months (8 Weeks)

Mode of Delivery

Online/ Face to Face

Online

Application

Programme Overview

Bioinformatics programme is designed to introduce biotechnologists to mathematical and computational representation to solve biological. Students will learn how to use the databases and alignment. Furthermore, they will learn about the biomolecular simulations, protein structure, and design drugs using bioinformatics tools. They also understand about protein-protein interactions. After completion of this course students can analyze complex problem of DNA, RNA and protein in a biological system. The course focuses on the theoretical insight as well as the practical skills using free open-source bioinformatics software to tackle common biological problems.

Learning Outcomes

On completion of the course participants should be able to:

  • Explain about the Bioinformatics, Bioinformatics databases, alignment, biomolecular simulations, protein structure, homology modelling, computer aided drug design and docking.
  • Perform practical in Bioinformatics.
  • Prepare assignment using a variety of resources.
  • Present orally on topics related to Bioinformatics.

Course Progression

Credits from this Micro-Credential Programme are transferable to the following full academic programme:

  • Master of Biotechnology

Assessments

  • Coursework 60%
  • Final Examination 40%

Study Plan for Micro-Credential in Bioinformatics

Week 1

Introduction to Bioinformatics

·         What is bioinformatics?

·         Principles of protein structure

 

Bioinformatics databases

·         Introduction

·         Nucleotide sequence databases

·         Protein sequence databases

·         Sequence motif databases

·         Protein structure databases

·         Other relevant databases

 

Lecture, practical

 

Week 2

 

Alignment

·         Similarity and Homology

·         Types of divergence

·         Conserved regions

·         Methodological principles

·         Substitution scores

·         Insertion/deletion scores

·         Statistical significance

·         Database search

·         Multiple alignment

·         Structure alignment

·         Structure alignment

·         Matching algorithms

·         Searching 3D databases

·         Classifying 3D shapes

Lecture, practical

 

Week 3

 

Biomolecular simulations

·         Basic concepts

·         Conformational sampling

·         Solvation

 

Protein structure

·         Introduction

·         Hydrogen bond

·         Experimental methods for protein structure determination

–  X-ray crystallography

– Nuclear magnetic resonance

  (NMR)

 

Lecture, practical

 

Week 4

 

Homology modeling

·         Homology Modeling

·         Threading Model

·         Evaluating Model

·         Web based homology modeling servers

 

Lecture, practical

 

Week 5

 

Computer aided drug design

·         Molecular bonding

·         Intermolecular forces

·         Thermodynamics

·         3D Protein structure

·         Enzymology

·         Mechanisms of enzyme action

 

Lecture, practical, tutorial

 

Week 6

 

Protein interaction

·         Basic concepts

·         Energy landscapes

·         Docking algorithms

·         Docking examples

 

 

 

Lecture

 

Week 7

 

Current issues in Bioinformatics

·         Future of Bioinformatics

·         Discussion on potentials and limitations

 

Lecture

 

Week 8

 

Final Examination

Conclusion Session

Awarding of Certificates

Presentation by VC or Representative of VC

 

Why Micro-Credential in Lincoln University College (LUC), Malaysia?

Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.

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