Micro-Credential in Advance Biochemistry
Programme Overview
Advanced Biochemistry is a postgraduate course that provides advance knowledge of biological molecules, process of metabolism and action along with their complex molecular interactions. This course equipped students with advance knowledge of biochemical processes of living cells and tissues as well as practical skills by handling advance experimental procedures of biological research. This module contributes some areas that are very important for solving of medical problems, and to the discovery and production of safe and effective drugs. This programme allows students to gain research experience in contemporary biochemistry, which may be a different area to their first degree, and professional skills, before deciding on a future career in industry or academic research.
Learning Outcomes
On completion of the course participants should be able to:
- Describe the chemistry of protein, stability and binding of protein, experimental methods for measuring binding, metabolism of macromolecules, signal transduction and human nutrition.
- Demonstrate the ability to carry out experiments in Advance Biochemistry.
- Present orally on Advance Biochemistry.
- Prepare assignment using a variety of resource materials.
Course Progression
Credits from this Micro-Credential Programme are transferable to the following full academic programme:
• Master of Biotechnology
Assessments
- Coursework 60%
- Final Examination 40%
Study Plan for Micro-Credential in Advance Biochemistry
Week 1 | Chemistry of Protein · Structures and chemical properties of amino acids · Protein purification and characterization · Protein structure · Protein Folding (Introduction / Tools to study folding – unfolding phenomenon) | Lecture
|
Week 2
| Stability and binding of protein · Contributions to protein stability and binding · Thermodynamics of Macromolecular Interactions · Mutagenesis · Identification of binding sites: – Protease protection – chemical methods – Mutational analysis – Protection interference – Affinity cleavage | Lecture
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Week 3
| Experimental methods for measuring binding: · Equilibrium diffusion · UV · Fluorescence · NMR · Spectroscopic methods (NMR,EPR, fluorescence) · X-ray crystallography
| Lecture, practical
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Week 4
| Metabolism of Macromolecules · Metabolism of carbohydrate: – Generation and storage of metabolic energy associated with carbohydrates – Mitochondrial electron transport chain and oxidative phosphorylation – Photophosphorylation § Krebs’ Cycle – Oxidative Phosphorylation – Glycolysis – Gluconeogenesis · Lipid metabolism – Fatty acids – general properties – ß- oxidation · Protein metabolism – Nitrogen Fixation and Assimilation – Amino Acid Biosynthesis · Nucleic acid metabolism – Chemistry and metabolism of purines and pyrimidines
| Lecture |
Week 5
| Signal transduction · Signal transduction · AMP activates protein kinase A · Signaling Monosaccharides · Mutagenesis
| Lecture
|
Week 6
| Human nutrition · Nutrition and food assimilation · Macronutrients and micronutrients · Vitamins and trace elements · Food and Fuel Metabolic Pathways · Free Energy in Metabolic Reactions
| Lecture
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Week 7
| · Practical · Determination of Competitive, non-competitive inhibitors · Thin layer chromatographic separation of sugars and membrane lipids. · Determination of Protein concentration · Separation and identification of · serum proteins by polyacrylamide/agarose gel · Identification and quantitation of activity of amylase · Identification and quantitation of activity of alkaline phosphatase
| Lecture, Practical |
Week 8
| Final Examination | Conclusion Session Awarding of Certificates Presentation by VC or Representative of VC
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Why Micro-Credential in Lincoln University College (LUC), Malaysia?
Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.