Micro-Credential in Fermentation Technology

Duration

2 Months (8 Weeks)

Mode of Delivery

Online/ Face to Face

Online

Application

Programme Overview

The course gives an idea of the relevance of biology in the industry with regards to the study and design of fermenters (mode of operations). Fermentation Technology emphasizes on the relevance of biological and engineering principles to problems concerning microbial, mammalian, biological and the biochemical systems. This course is essential to review fundamentals knowledge in fermentation processes, microbial growth kinetics, media for industrial fermentations, design of fermenters, instrumentation and control, agitation and aeration, recovery and purification of fermentation products as well as fermentation economics.

Learning Outcomes

On completion of the course participants should be able to:

  • Describe the fermentation processes, including the study and design of fermenters and microbial growth kinetics
  • Demonstrate the analytical and technical skills required for relevant fermentation processes in the laboratory
  • Demonstrate understanding of isolation, preservation and improvement of industrially important micro-organisms in a team
  • Present orally on Fermentation Technology

Course Progression

Credits from this Micro-Credential Programme are transferable to the following full academic programme:

  • Degree of Biotechnology

Assessments

  • Coursework 80%
  • Final Examination 20%

Study Plan for Micro-Credential in Fermentation Technology

Week 1

 

INTRODUCTION TO FERMENTATION TECHNOLOGY

·         Range of fermentation processes, microbial biomass

·         Microbial enzymes

·         Microbial metabolites

·         The chronological development of the fermentation industry

·         Components parts of fermentation process

 

KINETICS OF MICROBIAL GROWTH AND DEATH

·         Comparison of batch and continuous culture in industrial process

·         Effect of environmental conditions

Lecture

Tutorial

Week 2

 

INDUSTRIAL MICROORGANISMS 

·         Isolation, preservation and maintenance of industrial Microorganisms

·         Storage at reduced temperature

·         Storage in a dehydrated form

Practical 1

·         Formulation of culture media for fermentation process

 

MEDIA FOR INDUSTRIAL FERMENTATION

·         Typical media

·         Media formulation

·         Energy (carbon, nitrogen) sources

·         Growth factors

·         Oxygen requirement

·         Medium optimization

 

Oral presentation 1

 

Lecture

Practical

Presentation

Week 3

 

STERILIZATION

·         Development of inocula for industrial fermentation

·         Aseptic inoculation

 

Practical 2

·         The laboratory scale bioreactor (bench top fermenter)

 

Assignment 1

 

DESIGN OF A FERMENTER

·         Bioreactors

·         The agitator

·         The aeration system

·         Monitoring and control of various parameters

 

Mid -term test

 

Lecture

Practical

Assignment

Test

Week 4

 

INSTRUMENTATION AND CONTROL

·         Introduction to instrumentation

·         Methods of measuring process variables 

·         Online analysis of other chemical factors

AERATION AND AGITATION

·         Oxygen requirements for industrial fermentation

·         Determination of KLa values

·         Fluid rheology

·         Factors affecting KLa values in fermentation vessels

·         Effect of degree of agitation on KLa

 

Lecture

Tutorial

Week 5

 

DOWNSTREAM PROCESSING

·         Recovery and purification of fermentation products

·         Removal of microbial cells and other solid matters

·         Foam separation

·         Precipitation

·         Filtration

·         Centrifugation

·         Cell disruption

 

Practical 3

·         Downstream processing (solid -liquid separation)

 

 DOWNSTREAM PROCESSING

·         Liquid-liquid extraction

·         Solvent recovery

·         Chromatography

·         Membranes processes

·         Drying

·         Crystallization

 

Oral presentation 2

 

Lecture

Practical

Presentation

Week 6

 

EFFLUENT TREATMENT

·         Dissolved oxygen as an indicator of water quality

·         Treatment and disposal of effluents (physical, biological and chemical treatment)

·         Aerobic processes

·         Anaerobic treatment

Assignment 2

 

FERMENTATION ECONOMICS

·         Isolation of microorganisms of industrial interest

·         Strain improvement

·         Market potential

·         Effects of legislation on production of antibiotics and recombinant proteins

 

Practical 4

·         Downstream processing (purification)

 

Lecture

Assignment

Practical

Week 7

 

FERMENTATION ECONOMICS

·         Plant and equipment

·         Aeration and agitation

·         Heating and cooling

·         Continuous culture

·         Recovery costs

·         Water usage and recycling

·         Effluent treatment

 

Practical test

Lecture

Test

Week 8

 

Final Examination

Conclusion Session

Awarding of Certificates

Presentation by VC or Representative of VC

 

Why Micro-Credential in Lincoln University College (LUC), Malaysia?

Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.

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