Micro-Credential in Fermentation Technology
Programme Overview
The course gives an idea of the relevance of biology in the industry with regards to the study and design of fermenters (mode of operations). Fermentation Technology emphasizes on the relevance of biological and engineering principles to problems concerning microbial, mammalian, biological and the biochemical systems. This course is essential to review fundamentals knowledge in fermentation processes, microbial growth kinetics, media for industrial fermentations, design of fermenters, instrumentation and control, agitation and aeration, recovery and purification of fermentation products as well as fermentation economics.
Learning Outcomes
On completion of the course participants should be able to:
- Describe the fermentation processes, including the study and design of fermenters and microbial growth kinetics
- Demonstrate the analytical and technical skills required for relevant fermentation processes in the laboratory
- Demonstrate understanding of isolation, preservation and improvement of industrially important micro-organisms in a team
- Present orally on Fermentation Technology
Course Progression
Credits from this Micro-Credential Programme are transferable to the following full academic programme:
- Degree of Biotechnology
Assessments
- Coursework 80%
- Final Examination 20%
Study Plan for Micro-Credential in Fermentation Technology
Week 1
| INTRODUCTION TO FERMENTATION TECHNOLOGY · Range of fermentation processes, microbial biomass · Microbial enzymes · Microbial metabolites · The chronological development of the fermentation industry · Components parts of fermentation process
KINETICS OF MICROBIAL GROWTH AND DEATH · Comparison of batch and continuous culture in industrial process · Effect of environmental conditions | Lecture Tutorial |
Week 2
| INDUSTRIAL MICROORGANISMS · Isolation, preservation and maintenance of industrial Microorganisms · Storage at reduced temperature · Storage in a dehydrated form Practical 1 · Formulation of culture media for fermentation process
MEDIA FOR INDUSTRIAL FERMENTATION · Typical media · Media formulation · Energy (carbon, nitrogen) sources · Growth factors · Oxygen requirement · Medium optimization
Oral presentation 1
| Lecture Practical Presentation |
Week 3
| STERILIZATION · Development of inocula for industrial fermentation · Aseptic inoculation
Practical 2 · The laboratory scale bioreactor (bench top fermenter)
Assignment 1
DESIGN OF A FERMENTER · Bioreactors · The agitator · The aeration system · Monitoring and control of various parameters
Mid -term test
| Lecture Practical Assignment Test |
Week 4
| INSTRUMENTATION AND CONTROL · Introduction to instrumentation · Methods of measuring process variables · Online analysis of other chemical factors AERATION AND AGITATION · Oxygen requirements for industrial fermentation · Determination of KLa values · Fluid rheology · Factors affecting KLa values in fermentation vessels · Effect of degree of agitation on KLa
| Lecture Tutorial |
Week 5
| DOWNSTREAM PROCESSING · Recovery and purification of fermentation products · Removal of microbial cells and other solid matters · Foam separation · Precipitation · Filtration · Centrifugation · Cell disruption
Practical 3 · Downstream processing (solid -liquid separation)
DOWNSTREAM PROCESSING · Liquid-liquid extraction · Solvent recovery · Chromatography · Membranes processes · Drying · Crystallization
Oral presentation 2
| Lecture Practical Presentation |
Week 6
| EFFLUENT TREATMENT · Dissolved oxygen as an indicator of water quality · Treatment and disposal of effluents (physical, biological and chemical treatment) · Aerobic processes · Anaerobic treatment Assignment 2
FERMENTATION ECONOMICS · Isolation of microorganisms of industrial interest · Strain improvement · Market potential · Effects of legislation on production of antibiotics and recombinant proteins
Practical 4 · Downstream processing (purification)
| Lecture Assignment Practical |
Week 7
| FERMENTATION ECONOMICS · Plant and equipment · Aeration and agitation · Heating and cooling · Continuous culture · Recovery costs · Water usage and recycling · Effluent treatment
Practical test | Lecture Test |
Week 8
| Final Examination | Conclusion Session Awarding of Certificates Presentation by VC or Representative of VC
|
Why Micro-Credential in Lincoln University College (LUC), Malaysia?
Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.