Micro-Credential in Bioinformatics

Duration

2 Months (8 Weeks)

Mode of Delivery

Online/ Face to Face

Online

Application

Programme Overview

Bioinformatics involves the development and application of computational methods in biology, biotechnology and medicine, taking advantage of rapidly expanding databases. The course helps to understand the global availability of genome sequence information for human, animal, plant and micro-organism systems which has led to the development of new technologies. This course is essential to learn combined skills of molecular biology and computer science to exploit these data for the various applications of biotechnology. The topics included are genomics, DNA sequence data, experimental approach to genome sequence data genome information resources, computational genomics, sequence alignment & data base search, analysis of pair wise sequence alignment, FASTA files, BLAST, multiple sequence alignment, DATA base searching.

Learning Outcomes

On completion of the course participants should be able to:

  • Describe the fundamental principles of Bioinformatics
  • Demonstrate the use of bioinformatics software to analyze biological data
  • Discuss the biological aspects in bioinformatics in a group
  • Utilize suitable computational methods to solve biological problems
  • Prepare assignment using a variety of resource materials

Course Progression

Credits from this Micro-Credential Programme are transferable to the following full academic programme:

  • Degree of Biotechnology

Assessments

  • Coursework 80%
  • Final Examination 20%

Study Plan for Micro-Credential in Bioinformatics

Week 1

 

INTRODUCTION TO BIOINFORMATICS

  • Definition of Bioinformatics
  • Principles of Bioinformatics
  • DNA, RNA and protein structure

 

SEQUENCE AND SEQUENCE-RELATED

DATABASES

  • Introduction to data-bases
  • Nucleotide repositories
  • Common GenBank

 

Lecture

Tutorial

Week 2

 

SEQUENCE AND SEQUENCE-RELATED

DATABASES

  • Peptide repositories
  • Anatomy of a Uniprot entry
  • Other databases

 

SEQUENCE ALIGNMENT

  • Introduction to sequence alignment
  • Alignment between two sequences
  • Evolutionary models and alignment

scoring

Practical 1

  • Revision of nucleotide sequence

Chromatograms by Chromas   software

 

Lecture

Tutorial

Practical

Week 3

 

SEQUENCE ALIGNMENT

  • Dynamic programming and heuristics
  • Pairwise alignment strategies
  • Multiple sequence alignment

 

Practical 2

  • Sequence alignment and BLAST search by MEGA 6 program

 

Assignment 1

Oral presentation 1

 

PAIRWISE ALIGNMENT

  • Issues in sequence alignment
  • Homology, identity and similarity
  • Multiple sequence alignment
  • Phylogenetic tree

 

Mid-term test

 

Lecture

Assignment

Presentation

Test

Week 4

 

SEARCHING SEQUENCE-BASED

DATABASES

  • Introduction to searching in databases
  • Health warnings
  • Some terminology and consideration

 

SEARCHING SEQUENCE -BASED DATABASES

  • Searching sequences with sequences – generalities
  • Filtering and Masking
  • FASTA

 

Practical 3

  • Primer design-specific to an individual PCR nucleotide sequence by Primer 3

 

Lecture

Practical

Week 5

 

SEARCHING SEQUENCE -BASED DATABASES

  • Blast
  • Recent Blast scoring developments
  • Searching with profiles

 

BASIC TASKS IN BIOINFORMATICS

  • Examples of basic tasks
  • PCR primer design
  • Graphical viewing of data and annotation

 

Practical 4

  • Phylogenetic analysis- Phylogenetic tree & bootstrapping

 

Lecture

Tutorial

Practical

Week 6

 

GENERAL TIPS

  • Sequence formatting
  • Filenames
  • Data standards and data submission

 

GENERAL TIPS

  • Local versus remote, web-based software
  • Finding programs and documentation
  • Keeping track, keeping results and keeping up

 

Assignment 2

Oral presentation 2

 

Lecture

Assignment

Presentation

Week 7

 

CURRENT ISSUES IN BIOINFORMATICS

  • Future of Bioinformatics
  • Applications and disadvantages of Bioinformatics
  • Discussion on the potential and limitations

 

Practical test

Lecture

Test

Week 8

 

Final Examination

Conclusion Session

Awarding of Certificates

Presentation by VC or Representative of VC

 

Why Micro-Credential in Lincoln University College (LUC), Malaysia?

Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.

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