Micro-Credential in Basic Immunology
Programme Overview
The course will deal with components, functions, applications and the recent advances in the biology of the immune system and address its function in health and disease. The course is essential to achieve a comprehensive outline of the basics of immunology. This course will help students to acquire information regarding general the basic principles of immunology, antigen-antibody interaction, immunogenetics, vaccines, transplant, hypersensitivity, autoimmune diseases and clinically-oriented information. The Basic Immunology course is designed to offer thorough knowledge of the immune system with emphasis on the basic principles of immunology, antigen-antibody interaction, immunogenetics, vaccines, transplant, hypersensitivity, autoimmune diseases and clinical immunology.
Learning Outcomes
On completion of the course participants should be able to:
- Describe the immune system, including the key elements in the development, activation and regulation of the innate and adaptive immune system
- Execute relevant antigen-antibody interactions in the understanding of agglutination, complement fixation, precipitation and ELISA at laboratories
- Analyze the diseases caused by lack of immune regulation, including allergy, autoimmunity, cancer and the current/future treatment strategies using a variety of resource materials
- Present orally on Basic Immunology
Course Progression
Credits from this Micro-Credential Programme are transferable to the following full academic programme:
- Degree of Biotechnology
Assessments
- Coursework 80%
- Final Examination 20%
Study Plan for Micro-Credential in Basic Immunology
Week 1
| INTRODUCTION TO IMMUNOLOGY · Basic concepts in immunology · History and events in immunology · Overview and cells of the immune system · Innate and acquired immunity
INNATE IMMUNITY · Pattern recognition in innate immune system: Properties and components of innate immunity · The complement System · Induced innate responses to Infections · Role of innate immunity in stimulating · adaptive immune response
| Lecture Tutorial |
Week 2
| ADAPTIVE IMMUNITY · Properties and components of adaptive immunity · T cell-mediated immunity and cytotoxicity · Macrophage activation by armed CD4 Th1 cells · Humoral immune response · Role of antigens and cytokines in immune response Practical 1 · Blood grouping test-agglutination reactions
ANTIGENS · Meaning and properties of antigens (immunogens) · Immunogenicity and antigenicity · Interaction between the antibody and specific antigen (antigen recognition by Bcells)
Oral presentation 1
| Lecture Practical Presentation |
Week 3
| MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) · Gene organizations · Class I and Class II MHC molecules · Structure and functions, nature of polymorphisims in class I and class II MHC molecules · Antigen processing and presentation (antigen recognition by T -cells) Assignment 1
ANTIBODIES · Meaning and properties of antibodies (immunoglobulins) · Structure and classes of antibodies · Enzymatic digestion of antibodies. Monoclonal antibodies Mid -term test Practical 2 · Complement fixation test Sheep RBC suspension
| Lecture Assignment Practical |
Week 4
| IMMUNOGENETICS · Meaning of immunogenetics, scope and relevance of immunogenetics · Generation of antibody diversity
CYTOKINES AND THEIR ROLE IN IMMUNE REGULATION · Meaning and properties of cytokines · Classification of cytokine receptor · Categories of cytokines: interleukin (IL) interferon (IFN) tumor necrosis factor (TNF), colony stimulating factor (CSF), chemokine and growth factor (GF) · Biologic activity of cytokines
| Lecture Tutorial |
Week 5
| VACCINES AND IMMUNOTHERAPY · Meaning and types of immunity · Immunizing agents · Meaning and types of vaccination · Vaccination and immunization · Some hazards of immunization · Cold chain equipment
Practical 3 · Radial immune diffusion technique agar plate
TRANSPLANTATION · Meaning and types of transplant · Complications of organ transplantation · Meaning and types of rejection · Immunosuppression · Stem cells · Cell therapy and tissue engineering
Oral presentation 2
| Lecture Practical Presentation |
Week 6
| ALLERGY AND HYPERSENSITIVITY · Meaning and classes of hypersensitivity · Properties of allergens · Effector mechanisms in allergic reactions and IgE · Hypersensitivity diseases
Assignment 2
IMMUNODEFICIENCY AND AGING · Autoimmunity and autoimmune diseases · Classification of immunodeficiency states · Aging of the immune system
Practical 4 · Enzyme linked immunosorbent assay-DOT ELISA | Lecture Practical Assignment
|
Week 7
| FAILURES OF HOST DEFENSE MECHANISMS · How do pathogens evade the immune system? · Inherited immunodeficiency diseases · Acquired immune deficiency syndrome
Practical test
| Lecture Test |
Week 8
| Final Examination | Conclusion Session Awarding of Certificates Presentation by VC or Representative of VC
|
Why Micro-Credential in Lincoln University College (LUC), Malaysia?
Micro-credentials in Lincoln University College (LUC), Malaysia offer a flexible, targeted, and accelerated pathway of acquiring industry-relevant skills that meet the demands of today’s evolving job market. Designed for students, professionals, and individuals seeking to upskill or reskill, credentials offer learning experiences and formally recognized certifications, with enhanced employability, and serving as stepping stones to higher qualifications. LUC’s micro-credential programs are supported by strong academic frameworks and offer clear progression pathways into full-fledged degree programs. After completing this Micro-credential course, professionals can use their updated skills to apply for promotions or switch to a different job role.